Cystic fibrosis (CF) is a lethal hereditary disease caused by loss-of-function mutations of the chloride channel cystic fibrosis transmembrane conductance regulator (CFTR).With the development of small-molecule CFTR modulators, including correctors that facilitate protein folding and expression and potentiators that promote channel activity, about
Hemophilia is an X-linked recessive genetic disorder which affects approximately 400,000 people globally.Differing healthcare reimbursement systems, budgetary constraints and geographical and cultural factors make it difficult for any country to fully deliver ideal care.Although developed countries have sufficient treatment products available, they
Abstract We study the pseudo-spin density Ball - Bat - Baseball BBCOR response of a disordered two-dimensional spin-polarized Bose gas to weak alternating magnetic field, assuming that one of the spin states of the doublet is macroscopically occupied and Bose-condensed while the occupation of the other state remains much smaller.We calculate spatia
Abstract As machine learning (ML) continues to advance in the field of materials science, the variation in strategies for the same steps of the MedicalGear ML workflow becomes increasingly significant.These details can have a substantial impact on results, yet they have not received the deserved attention.This review aims to explore the various str